Looking to derail comprehensive immigration talks on Capitol Hill, the advocacy group NumbersUSA launched a new ad campaign Wednesday targeting Alaska Sen. Mark Begich, who is seen as one of the most vulnerable Democrats up for re-election in 2014.

The ad is part of the group's "Say No to Amnesty" campaign (https://www.saynotoamnesty.com/), which also has targeted Sen. Lindsey Graham, South Carolina Republican, who is a member of the bipartisan "Gang of Eight" that is hammering out a comprehensive immigration bill that could provide legal status as well as a path to citizenship for the estimated 11 million illegal immigrantsliving here.